Risedronate also is known by the brand names Actonel and Atelvia. It is a bisphosphonate derivative and used in the treatment of osteoporosis. A typical dosing regimen is 35 mg PO every week. Alternative dosing regimens are 5 mg PO qd and 150 mg PO every month. Risedronate works by inhibiting resorption of bone which indirectly leads to an increase of bone mineral density (BMD). Unlike other drugs, risedronate is not metabolized. This medication has an extremely long half-life at around 480-561 hours. When taking risedronate it is important to consider adequate Calcium and Vitamin-D intake. Common side effects are abdominal pain, insomnia, depression, constipation, dyspepsia, and headache. When taking risedronate it is important for it to be given with 6-8 ounces of water and for the patient to remain upright for at least 30 minutes. 

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